细胞生长和增殖的调控一直是细胞生物学领域的核心问题，而且与细胞分化及命运决定、个体发育和肿瘤发生都密切相关。本实验室主要以哺乳动物细胞为材料，利用高分辨率活细胞荧光成像、蛋白质组及其磷酸化组、高通量遗传筛选和其它多种手段来探讨细胞生长和增殖的调控机制及其跟疾病的关联。具体研究方向为：

1. 细胞如何感知外在的营养物质、生长因子或压力的变化；

2. 纤毛作为特定细胞器如何应对并且影响细胞生长和增殖信号；

3. 探索纤毛、细胞生长增殖和疾病的联系。

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